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Technology
Three platform technologies, each developed in-house from vaccine and drug-delivery research, each protected by patents and in commercial production.

A new substance: oxygen held inside water.
The WOX process binds O₂ molecules inside a lattice of water molecules. The result is a substance in its own right, oxygen clathrate hydrate, granted substance patents in the United States and China in 2021 and in Japan in 2022.
Because the oxygen is held rather than dispersed, it does not escape when the bottle is opened and it does not react with other components. WOX is designed to be taken in with water through the digestive tract, a route to oxygen intake other than the lungs.
WOX stays stable at high and low temperatures, which opens it to a wide range of products and industries.
| Substance | Oxygen clathrate hydrate |
|---|---|
| Ingredients | Water, oxygen |
| Dissolved oxygen | Stable above 50 ppm |
| Temperature | Can be frozen or boiled |
| Production | WOX® manufacturing units No. 1–4, 2015–2024 |
| Substance patents | US 10,913,037 B2 · JP 7087235 · CN ZL 2015 8 0071029.1 |
not to scale



Sports and active lifestyles
Used by professional athletes in Japan around training. Placebo-controlled research on blood flow and SpO₂ is published.
Skin care
WOX is the base of our CORGRACE® mists, masks and creams, delivering oxygen and moisture to the skin.
Food and beverage
Stable through freezing and heating, so it can be used as an ingredient in food production.
Life-science research
Early work on oxygenated water in cell culture and pharmaceutical development, including vaccines.


Clean without alcohol or harsh chemicals.
HT Silver keeps nano-silver stable in water, so it does not discolor or lose effect. The result is an antibacterial, antiviral and antifungal solution that contains no alcohol.
Frequent use of alcohol sanitizers or harsh soaps leaves hands dry and rough. HT Silver is gentle enough for everyday use on skin, and it does not rust metal or damage plastic, paint, wood or varnish.
| Performance | Antibacterial, antiviral, antifungal |
|---|---|
| Alcohol | None |
| Surfaces | Skin, metal, plastic, painted surfaces, wood, upholstery |
| Settings | Homes, gyms, schools, clinics |
| Also used as | Preservative alternative in skincare |
From skin-applied vaccines to skin care.
Our founder helped develop a vaccine that could be applied to the skin instead of injected. The same delivery science became 4DDS, a four-dimensional delivery system that carries ingredients to where they are needed and releases them gradually.
4DDS is a special liposome with a positively charged protein surface. Active ingredients sit in separate layers and are released one layer at a time, from the outside in, so they keep reaching the target area.
- 2008Fourth-generation liposome, CORGRACE® series
- 2015Fifth-generation liposome
- 2025Oxygen liposome ingredient
- NextSixth-generation nanocapsule, in development



Measuring oxygen that ordinary meters miss.
Standard dissolved-oxygen meters measure free oxygen. Oxygen held in clathrate form does not fully register, so conventional instruments undercount it.
We developed and patented a total dissolved-oxygen method that releases and measures the held oxygen. Every WOX specification is stated on this basis, and the method is patented in the United States, Japan and China.

