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A research and manufacturing company in Kawasaki, Japan, working since 2004 on one question: how to get more oxygen to where the body needs it.
Twenty years on the problem of oxygen.
The body needs oxygen to function, recover and heal, yet the lungs are its only way to take oxygen from the environment. Inflammation, illness and environmental factors can all limit them. Scientists have long looked for a stable, scalable way to deliver oxygen by another route.
I began my career as a medical doctor and moved into research on treatments and diagnostics for infectious diseases, then into vaccine development, including a vaccine that could be painted onto the skin. That work showed us that the same delivery science had uses in medicine and cosmetics.
I founded MediScience Espoir in 2004 to develop technologies that improve quality of life for people everywhere. In 2011 we launched WOX, the gas–liquid fusion of oxygen and water. Since then we have obtained manufacturing and measurement patents, substance patents in the United States, China and Japan, and opened a second production site in Tottori.
If you want to develop or improve a product with our technology, we would like to hear from you.
Takaaki MatsumotoMD, PhD, Pharmacist · Founder and Representative Director
What we hold ourselves to.
Our mission is to contribute to the health and well-being of people.
We pursue high-value products that bring beauty and health to our customers.
We care for the health of our staff and seek the company’s prosperity and the happiness of everyone who works here.
We aim to lead in improving quality of life by delivering the safe, high-quality products people are waiting for.
Kawasaki Eruboshi, for advancing women in the workplace (2026) · Kanagawa “Ganbaru” Company (2019) · Corporate value certification (2019) · Higashikuninomiya Award (2016) · Kawasaki Entrepreneur Audition awards (2010, 2022)
Physicians, pharmacists and veterinarians.
Every product is evaluated by a team of around ten specialists across medicine, dentistry, veterinary science, pharmacy, nursing, biology and agricultural chemistry.
Takaaki Matsumoto
MD, PhD, Pharmacist · CEO
Infectious-disease drugs and diagnostics at Kyowa Hakko; skin-applied and cancer vaccines at Pasteur Mérieux Connaught.
Toshikatsu Hagiwara
DVM, PhD (Agriculture) · Technology Development
Infectious-disease research at a Ministry of Health institute; JICA expert in Africa and Southeast Asia.
Miyako Matsumoto
MD, PhD · Safety Management
37 years on respiratory viruses and national vaccine testing at a Ministry of Health institute. Oversees product safety and manufacturer audits.
Seitaro Shimizu
Product and Technology Development
Cosmetic formulation with high WOX content, built on current dermatology and quality stability.
2004 to today.
Selected milestones. Grants from Japan’s Ministry of Economy, Trade and Industry and Kanagawa Prefecture have supported each generation of our manufacturing units.
- 2004
- Founded in Kawasaki on June 4
- 2008
- Fourth-generation liposome commercialized (CORGRACE® series)
- 2010
- PQ Lab opened at the Kawasaki New Industry Creation Center
- Four awards at the Kawasaki Entrepreneur Audition
- 2011
- WOX® oxygen delivery water and its manufacturing device developed and launched
- 2014
- WOX Co., Ltd. established as sales company
- QOL Support Research Council incorporated as a nonprofit · TEAM WOX formed
- 2015
- Fifth-generation liposome · WOX® manufacturing unit No. 1
- Manufacturing patents (U.S., Japan) and measurement patents (U.S., Japan, China)
- 2016
- Higashikuninomiya Award · CORGRACE® Vector Pack · unit No. 2 (METI grant)
- 2017
- CORGRACE® WOX-sui launched · unit No. 3 (METI grant)
- 2019
- Certified as a Kanagawa “Ganbaru” company · corporate value certification
- 2020
- HT Silver 10, AG WOX 10 and CORGRACE® WOX Moisture Neo launched
- 2021
- Substance patents granted in the United States and China
- 2022
- Substance patent granted in Japan
- 2023
- CORGRACE® WOX Hair & Scalp Essence and WOX Oxygen Mist Serum launched
- 2024
- WOX® manufacturing unit No. 4 (Kanagawa Prefecture grant)
- 2025
- Daisen Factory, Tottori, begins operation · WOX® 8 L and dispenser
- Oxygen liposome cosmetic ingredient launched
- 2026
- New HT Silver · WOX400 ingredient · WOX Gummy Cap · “Kawasaki Eruboshi” certification
MediScience Espoir Inc.
Research, manufacturing and quality control. Sales and marketing through our group company, WOX Co., Ltd.
| Company name | MediScience Espoir Inc. |
|---|---|
| Representative | Takaaki Matsumoto, MD, PhD, Pharmacist |
| Established | June 2004 |
| Business | Development of new products and materialsDevelopment, manufacturing and sales of WOX® oxygen delivery water, HT Silver antibacterial and antiviral products, CORGRACE® skin care and SILVION oral care · OEM manufacturing of quasi-drugs and cosmetics |
| Licenses | Quasi-drug manufacturing 14DZ200064 · marketing 14D0X10009 Cosmetics manufacturing 14CZ200124 · marketing 14C0X10019 |
| Group | WOX Co., Ltd.Supports the nonprofit QOL Support Research Council |
| Banks | Sumitomo Mitsui Banking Corporation · The Bank of Yokohama · MUFG Bank · Kawasaki Shinkin Bank |
Kawasaki
2-502, 1-2 Shin-Tsukagoshi, Saiwai-ku, Kawasaki, Kanagawa 212-0027, Japan+81-44-511-2214